Arkansas State University, Arkansas Biosciences Institute/ College of Agriculture and Technology
- Synthetic Biology, Bioprocess and Metabolic Engineering
Sivakumar’s lab is currently focused in two major industrial research areas: A) Natural anticancer drug development, and B) Renewable bioenergy. Both researches are collaborated with multinational pharmaceutical and energy industries. Our long term goals are to build on the innovation and discoveries of: 1) plant-made potential anticancer medicine, while preventing side effects; and 2) to develop a next generation clean alternative energy and hydrocarbon sustainability. Sivakumar’s lab provides a unique opportunity to explore pharmaceutical and energy research.
Sivakumar G, Jeong K, Lay JO (2014). Bioprocessing of Stichococcus bacillaris strain siva2011. Biotechnology for Biofuels, 7: 62.
Sivakumar G, Jeong K, Lay JO (2014). Biomass and RRR-α-tocopherol production in Stichococcus bacillaris strain siva2011 in a balloon bioreactor. Microbial Cell Factories, 13: 79.
Sivakumar G (2013). Colchicine semisynthetics: Chemotherapeutics for cancer? Current Medicinal Chemistry, 20: 892-898.
Sivakumar G, Xu J, Thompson RW, Yang Y, Randol-Smith P, Weathers PJ (2012). Integrated green algal technology for bioremediation and biofuel. Bioresource Technology, 107: 1-9.
Sivakumar G, Medina-Bolivar F, Lay JO, Dolan MC, Condori J, Grubbs SK, Wright SM, Baque MA, Lee EJ, Paek KY (2011). Bioprocess and bioreactor: Next generation technology for production of potential plant-based antidiabetic and antioxidant molecules. Current Medicinal Chemistry, 18(1): 79-90.
Ge X, Burner DM, Xu J, Phillips GC, Sivakumar G (2011). Bioethanol production from dedicated energy crops in Arkansas, USA. Biotechnology Journal, 6(1): 66-73.
Sivakumar G, Liu C, Towler MJ, Weathers PJ (2010). Biomass production of hairy roots of Artemisia annua and Arachis hypogea in a scaled-up mist bioreactor. Biotechnology and Bioengineering, 107(5): 802-813.
Sivakumar G, Vail DR, Xu J, Burner DM, Lay JO, Ge X, Weathers PJ (2010). Bioethanol and biodiesel: Alternative liquid fuels for future generations. Engineering in Life Sciences, 10(1): 8-18.
Sivakumar G, Vail DR, Nair V, Medina-Bolivar F, Lay JO (2009). Plant-based corosolic acid: Future anti-diabetic drug? Biotechnology Journal, 4(12): 1704-1711.
2011-2014 Natural anticancer molecules: Bioprocess engineering and bioassay, Arkansas Biosciences Institute (# 262178)
2011-2012 Judd Hill Foundation (# 159004)
2010-2012 Department of Energy (# DE-FG36-08BO88036)
2009-2010 National Science Foundation Arkansas EPSCoR (09-EPSCoR-0086)
2008-2009 Department of Energy (# DE-FG36-08BO88036)
- Anticancer Drug Development
- Analytical Chemistry/ HPLC-MS and GC-MS
- Natural products/Biopharmaceuticals
- Industrial Bioreactors/Root Culture
- Metabolomics/Metabolic Engineering
- Transcriptomics/Genomic de novo Assembly
- Hydrocarbon Upstream/Downstream Processing
- Bioenergy and Bio-based Products